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Abbreviations BS: Beighton score cEDS: Classical Ehlers-Danlos syndrome clEDS: Classical-like Ehlers-Danlos syndrome CTP: Connective tissue panel EDS: Ehlers-Danlos syndrome gJHM: Generalized joint hypermobility HCTD: Heritable connective tissue disorder hEDS: Hypermobile Ehlers-Danlos syndrome JHM: Joint hypermobility LOVD: Leiden Open Variation Database MLPA: Multiplex ligation-dependent probe amplification MRI: Magnetic resonance imaging MVP: Mitral valve prolapse NGS: Next generation sequencing NMH: Neurally mediated hypotension POTS: Postural orthostatic tachycardia syndrome QoL: Quality of life SD: Standard deviation vEDS: Vascular Ehlers-Danlos syndrome References Malfait F, Francomano C, Byers P, Belmont J, Berglund B, Black J, et al

The speaker states that his last cigarette was sent out of his car window One night, years ago